Biologist - Nuclear Receptors Research

Company: University of California, San Francisco

Position Title: Biologist - Nuclear Receptors Research / Pharmaceutical Chemistry

Department: Pharmaceutical Chemistry 

Location: Mission Bay

Position Type: Full Time

Percentage: 100%

Work Days/Shift: Monday - Friday

Requisition #: 76000BR

Job Summary: 

Dr. England’s research laboratory (https://pharm.ucsf.edu/england) is developing small molecules to control the activity of nuclear receptors, a class of ligand-regulated transcription factors that play critical roles in human health and disease. The Biologist will characterize the effects of small molecules on the activity of nuclear receptors using cellular assays, including luciferase reporter assays and gene transcription assays (RTqPCR), work up and analyze data (including statistical analyses).

Other aspects of the project may involve developing DNA constructs to explore various aspects of nuclear receptor functioning in cells and characterizing ligand effects on the localization and trafficking of nuclear receptors using appropriate microscopic imaging tools and techniques. Must have prior research laboratory experience, be proficient in aseptic techniques, and be willing/able to design and troubleshoot experiments.

Department Description: The Department of Pharmaceutical Chemistry is one of three departments in the UCSF School of Pharmacy and is under the administrative oversight of the Department Chair, Michelle Arkin.

Through research and teaching, the Department seeks to understand the biological principles of small molecules, proteins, and cellular design, and to apply these principles for the therapeutic benefit of patients

Required Qualifications:

• BA/BS in related science including one year of recent/directly related work experience utilizing the techniques/methods required by the position; and/or equivalent experience/training
• Hands-on research experience working with cultured and/or primary cells and carrying out cellular assays in a research laboratory (college laboratory courses are not sufficient)

Preferred Qualifications:        

• PhD in cellular and molecular biology or related field

About UCSF

In order to be considered for open positions at UCSF, you will need to submit your resume through our online application process.  Once you complete the online application process, you will receive an email confirming that your submission has been received.  Submitting your resume to UCSF opens the door to many immediate and ongoing job opportunities. Your resume will remain active in our applicant database and you will be able to update it as needed.

To submit your resume online go to: https://jobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&partnerid=6495&siteid=5861&Areq=76000BR

Emailed applications are not accepted.

Apply specifically to requisition # 76000BR. 

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.