PREP0004170 Mass Spectral Software Analyst

Mass Spectral Software Analyst/Programmer

Project Description:

The Materials Measurement Laboratory of the National Institute of Standards and Technology is seeking qualified candidates (U.S. Citizens preferred) to maintain and develop widely used software and analysis methods for reference databases of mass spectra and related data. This involves highly complex Microsoft Windows user interface software for both internal and external use in accessing this data as well as for identifying compounds in complex chemical mixtures. It also involves developing software specifically designed for mass spectral data quality analysis. Spectra include electron ionization with retention indices, tandem electrospray of small molecules and peptides. This work also involves the implementation of chemical structure-based analysis as well as the building of varied library analysis tools to assist NIST research programs.

Key Responsibilities: 

• Maintain and extend a highly complex Microsoft Windows user interface program for enabling the use of NIST Mass Spectral Reference Libraries for compound identification
• Maintain and extend user interfaces and data analysis algorithms for interpreting mass spectra in terms of chemical structure
• Create consensus mass spectral libraries for specialized NIST applications
• Create interfaces between programs written by other NIST staff and external distributors of NIST data to the NIST library program

Desired Qualifications: 

• U.S. Citizen Preferred
• Ph.D. Required
• Demonstrated expertise in developing highly interactive, complex Microsoft Visual C++chemical structure based scientific database software
• Demonstrated expertise in chemical structure analysis by computer
• Demonstrated facility in applying mass spectral fragmentation rules for electron ionization, electrospray tandem, and related ionization methods

Other Details:

• Full-time: the participant is expected to work 40 hours a week
• Location: the participant will work at the NIST Gaithersburg Campus.
• Duration: this is expected to be a one-year position. Extensions are sometimes granted depending on the availability of funds.