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Intern- Downstream Process Development

Position Summary

 

The Downstream Process Development Intern will help to implement in-process analytical tools for AAV characterization. The project will involve comparing and correlating data generated from different analytical methods as well as streamlining data entry. This will include evaluating different assays used to quantify product titer, stability, and purity of process and drug substance samples and automating data collection. The intern will also assist in the production of recombinant AAV by learning about and assisting in the execution of various downstream unit operations.

 

This position is located in RTP, NC and will report to a Senior Research Associate, Process Development.

 

Job Responsibilities

  • Support the downstream process development team in the execution of experiments and purification of recombinant AAV
  • Learn about various downstream unit operations and analytical assays used for product characterization
  • Participate in an individual project to implement in-house analytical tools
  • Communicate findings with other lab members
  • Develop tools to streamline input and analysis of data
  • Present results in a final formal presentation to the process development group

 

Minimum Requirements

  • Pursuing at least a BS degree in scientific or engineering related field
  • Must be at least a Junior in university at the time of your application
  • Basic understanding of downstream purification techniques (e.g. lysis, chromatography, filtration, fill/finish)
  • Basic understanding of analytical methods used to characterize AAV (SEC-HPLC, ELISA, qPCR, DLS etc.)
  • Proficient with MS Office Suite and ability to learn new platforms quickly (JMP statistical software)
  • Strong sense of accountability and ability to prioritize multiple tasks
  • Excellent organizational skills and attention to detail
  • Proactive and solution-driven mindset
  • Strong sense of accountability and ability to prioritize multiple tasks
  • Excellent organizational skills and attention to detail
  • Flexible and willing to support a variety of tasks for the downstream PD team
  • Available to work full-time at the office during the summer months (May-August) at an AskBio office

 

Preferred Education, Experience and Skills

 

  • Students pursuing a Master’s degree in a scientific or engineering field are encouraged to apply
  • Experience analyzing and interpreting data from assays characterizing biopharmaceutical products.
  • Prior internship, work, or volunteer/extracurricular experience in the biopharma industry
  • Prior experience working in a lab environment
  • Prior hands-on experience in biomanufacturing
  • Advanced experience with Excel/VBA scripting

 

 

 

AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.

 

 

Agencies:  Please do not contact any employee at AskBio about this requisition.  Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position.  All agencies must have a prior executed service agreement with AskBio prior to any search engagement.  If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.