Molecular Genetic Laboratory Technologist
Title:
Molecular Genetic Laboratory Technologist II
Company Overview:
About SignatureDx:
In collaboration with the University of Pittsburgh and Magee-Womens Research Institute and Foundation, Signature is focused on the research and development of diagnostic and phenotyping tools for early-stage complex disease. In addition to its research facilities at Magee-Womens Research Institute, Signature operates SDxLabs, a CLIA certified high complexity molecular diagnostic laboratory that is both CAP and COLA Accredited.
Our Mission:
Signature is changing the paradigm of disease detection through new advanced technologies and novel diagnostic tools. Using a framework of noninvasive liquid biopsy to understand states of cellular function, Signature is focused on early detection of silently progressing complex disease. Signature is also dedicated to supporting women’s reproductive health by utilizing genetic tests to determine risks of pregnancy-related complications before they occur.
Our Approach:
Our approach utilizes novel lab techniques to process liquid biopsy samples that are then analyzed using pioneering algorithms and machine learning. This noninvasive screening method can serve as an early indication system by informing current disease state, and the likelihood of future disease development. This could reduce the expense, discomfort, and risks of traditional diagnostics. Using early detection as a means of proactive healthcare has the potential to drastically reduce the progression of organ disease and pregnancy-related complications.
Job Description:
As a Molecular Genetic Laboratory Technologist you will assist in the day-to-day clinical laboratory operations. The Molecular Genetic Laboratory Technologist will independently and accurately perform high complexity molecular diagnostic tests. You will be responsible for performing all molecular lab procedures from start to finish according to standard operating procedures, analyzing results, and troubleshooting technical problems pertaining to specimen adequacy, laboratory data, and instrumentation.
Essential Duties and Responsibilities:
- Adhere to documented standard operating procedures for all aspects of laboratory work. Ensure that all relevant information concerning samples is recorded, samples are handled correctly, and that all necessary records and quality data are maintained.
- Adhere to all safety guidelines, including the appropriate use of Personal Protective Equipment (PPE).
- Maintain patient/client confidentiality.
- Evaluate specimens received by SDxLabs and organize workflow to provide optimum efficiency of testing and turnaround time of results.
- Use the Laboratory Information System to properly track patient specimens throughout the testing process.
- Perform data analysis according to standard operating procedures to generate patient results.
- Perform quality control, validation, and other quality activities to verify performance of clinical assays.
- Prepare reagents and solutions in accordance with established guidelines.
- Maintain equipment by performing assigned calibration and maintenance activities. Troubleshoot unexpected problems with equipment.
- Operate complex equipment and computer programs related to equipment and Laboratory Information System.
- Aide in the research and development of new molecular assays from validation to SOP generation.
- Conduct research to assist in the planning, modification, and design of experiments.
- Maintain an organized and clean work environment.
- Maintain inventory of supplies and reagents and communicate order needs.
- Directly assist laboratory management in the preparation for all inspections by accrediting agencies.
- Assist in research and development of new molecular assays from validation to SOP generation.
- Assists in the training of new employees and current employees.
- Participate in educational activities and stay up to date on all required training.
- Perform any other job-related duties as assigned.
Requirements:
- Bachelors’ Degree in medical technology, clinical laboratory, chemical, physical or biological science.
- Minimum of 3 years lab experience performing molecular laboratory procedures in a high complexity testing environment. Molecular experience to include the performance of high complexity molecular techniques including DNA/RNA extraction, Real-Time PCR, Reverse-Transcriptase PCR, and data analysis and interpretation.
- Experience designing and conducting wet lab processes and genetic testing workflows.
- Experience working in a CAP/COLA accredited lab preferred.
- Must possess excellent pipetting skills (single and multi-channel) and thorough understanding of aseptic technique.
- Ability to organize workflow and lead other team members.
- Strong interpersonal skills with the ability to interact with individuals from a variety of levels and functions.
- Eagerness to learn and grow.
- Ability to work independently.
- Pleasant and positive attitude.
- Excellent written and verbal communication skills.
- Familiarity with Next Generation Sequencing techniques preferred.
- Familiarity with ThermoFisher QuantStudio (5, 12K flex or similar), KingFisher, Illumina sequencers preferred.
- Experience using Microsoft Office Suite of applications. Proficient in Microsoft Excel.
- Must pass background check.
Pay:
- $20-$28 Per Hour
Benefits
- PTO
- Dental
- Healthcare
- 401k Match
- Paid Holidays
- Identity Theft Insurance
- Disability Life insurance
- Professional Development
Travel
- <25%
EEOC Statement:
SignatureDx is an Equal opportunity Employer which means it will comply with all laws prohibiting discrimination against employees and applicants based on race, color, religion, sex, sexual orientation, gender identity, gender expression, age, national origin, citizenship status, disability, genetic information, or veterans' status.